CTCC Chemicals for supplies and commercial agancies
Pharmaceuticals Industry Overview
CTCC-csca is a trading organization whose global operations are built around the needs, priorities and objectives of our pharmaceutical Raw Material clients.
Our commitment to you is a cornerstone of our business. The Crown-chem network consists of established facilities with the capabilities, experience and quality track records that come with supplying large-scale commercial products to global partners Our client-centered approach has enabled us to support various market and supply chain segments,
At CTCC-csca, we are committed to meeting your aseptic liquid filling and sterile pharmaceutical manufacturing needs and priorities across every stage of your sterile fill-finish project.
The pharmaceutical industry raw materials faces many constraints and has different specialties, making it stand completely on a different scale than any other industry types. Pharma industry needs extreme precision and care in each step ranging from collecting the pharma raw materials to get in hand the ready product for the supply.
Let us get in-depth details about the raw materials used in the pharmaceutical industry. The categorization distinct the raw materials from each other.
Generally, Pharmaceutical Raw Materials can be categorized into the following three categories:
1. Active Pharmaceutical Ingredients (APIs)
2. Inactive Ingredients or Excipients
3. Packaging Raw Materials
PHARMACEUTICAL RAW MATERIALS OF ACTIVE PHARMACEUTICAL INGREDIENTS (APIS)
API is one of the main parts of the pharma drug, which is pharmaceutically active and is responsible for the drug action. Accuracy and Precision with the raw materials are two main must aspects for while making API.
Strengths of APIs: There are certain standards to determine APIs strength in each drug. Manufacturers are required by the FDA to prove their products potency in labs as well as in real life through patients.
Active Pharmaceutical Ingredients global market is predicted to reach $198.8 billion by 2022 with a CAGR of 6.4%. The main factors driving this growth are patent expiration, initiatives by govt., penetration, and increase in the aged population.
The largest API manufacturers are in Asia, in India and China particularly.
PHARMACEUTICAL RAW MATERIALS OF EXCIPIENTS
Excipients also called as inactive ingredients or drug carriers. Pharma raw materials used as excipients consist of solvents and other such carriers. Excipients bring bulkiness and stability in the drug formulation, along with facilitating absorption and preventing denaturation of drugs.
There are guidelines by international pharmaceutical standards for the materials to get qualified as an excipient.
Industry analysts have forecast the excipients market to reach CAGR of 6.53% by 2021 to reach $7.7 billion by 2022 globally. According to reports produced by ASD, excipients global market is being driven through rising oral drugs consumption.
North America has the largest pharmaceutical excipient market share, because of the presence of large excipients manufacturers here and rising pharmaceutical drugs demand. Europe has the second largest share followed by the Asia Pacific.
PHARMACEUTICAL RAW MATERIALS OF PACKAGING
Packaging in the pharmaceutical industry also need to be perfect and precise. Raw materials used for packaging in the pharmaceutical industry includes plastics, polymer, glass, aluminum foil, paper and more. Packaging is made a separate category for the pharma because of the use of diversified raw materials.
The global pharmaceutical packaging market demand is estimated to reach above $80bn by 2020. North America and Europe regions have the major share in pharmaceutical packaging materials market.
Advancement in drug delivery technologies is initiating the use of innovative packaging in pharmaceutical sector, increasing the demand for varied packaging materials.
Raw chemical materials for the pharmaceutical industry are materials of a particularly high quality. Strict requirements for these intermediate products relate not only to their purity, but also to the specific technical parameters resulting from their specific production process. For this reason, it is worth cooperating with manufacturers of raw pharmaceutical materials, such as PCC Group, who apply production standards in line with the recommendations of the International Organization for Standardisation (ISO). This organisation is involved in many regulatory areas, which includes the definition of requirements for environmental management standards (ISO14000) and quality management systems (ISO9001). PCC Group produces all their raw materials for the pharmaceutical industry in accordance with these ISO standards and the requirements of the latest version of the European Pharmacopoeia (version 9.0).
CTCC Group, is a trader of nearly 1,000 chemical products for industry, including the pharmaceutical market. Their offer includes both pharmaceutical raw materials and excipients from the CTCC group such as Macrogol Cetostearyl Ether, Macrogolglycerol Hydroxystearate (PEG-40 Hydrogenated Castor Oil) and Macrogolglycerol Ricinoleate. Among the products dedicated to the pharmaceutical industry, they also provide high-purity hydrochloric acid and caustic soda. These ingredients are used to produce ointments, creams, gels, emulsions, capsules or tablets. CTCC Group’s portfolio also includes high-quality raw materials for API synthesis, including monochlorobenzene (MCB), orthodichlorobenzene (ODCB), and phosphorus trichloride and phosphorus oxychloride.
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CTCC-csca offers the world's largest portfolio and variety of chemical raw materials to meet the specific needs of your API production.
List of Chemicals Used in Pharmaceutical Industry
Chemicals contribute to many fields in industry, including pharmaceutical industry. Pharmaceutical industry is an industry of medicine and health care product. Either organic or inorganic compound have some benefits to human health. As this industry revolves around health, surely strict and thorough procedure is needed in order to create the safest with the least side effect of pharmaceutical products.
To know more about which substance or chemical in pharmaceutical products, here is the list of chemicals used in pharmaceutical industry.
1. Paracetamol (Acetaminophen)
One of the most common chemicals used in pharmaceutical industry is paracetamol. Paracetamol also known as acetaminophen is a painkiller as well as cure to fever. It has been used widely in commercial and generic medicine. The reason why paracetamol is very common is because it is one of the safest with the least side effects.
Thus, paracetamol is safe in recommended dose and it is rare for the side effect to occur compared to other painkiller. Some pharmaceutical products that contain this chemical are headache painkiller, toothache painkiller, fever cure for kids and moderate painkiller. Also, the price of paracetamol is relatively cheap, making it easier for people to find it.
2. Diclofenac
Diclofenac or sodium diclofenac is one of the most common over the counter products. The chemical itself is a non steroid inflammatory drug. It has two functions as anti inflammatory drug as well as medium pain killer. As for the distribution in pharmaceutical industry, diclofenac can be either topical or oral drug.
The most common use of it is as painkiller for joint pain and toothache. The anti inflammation effect is also good for healing wound and infection. Diclofenac comes in various dose with various effect. However, high dose of it may cause some side effect from sleepiness to nausea.
3. Dexamethasone
An anti-inflammatory drug that often prescribed with other drugs is dexamethasone. Dexamethasone is a corticosteroid medicine that has anti inflammation effect. The use of it in the right dose has many benefits such as helping to relieve infection, asthma, rheumatic, nerve inflammation and many more.
However, it also has many side effects from increasing glucose in blood stream to decline in immune system. Thus, the dose of dexamethasone is only allowed with guidance of expert. This substance often serves as accompaniment of other, more critical medicine to treat serious illness. Doctor advised the use of it only until the illness cured and not for prolonged, non-diagnosed use.
4. Antalgin
Another common painkiller widely produced by pharmaceutical industry is antalgin. Antalgin is a painkiller often people use to treat headache, toothache, rheumatic and nerve pain. It is often also found in analgesic products. As the side effects tend to appear after prolonged use, antalgin is more common in a generic medicine sold as over the counter medicine for short period of use only.
The side effects that can occur from excessive use of antalgin is decline in immune system, increased heart rate, and decrease of white blood cell. Thus, it is best to use products with antalgin substance for emergency only and not as regular medicine.
5. Sibutramine
A currently popular product from pharmaceutial industry is diet pill. One of chemicals that acts as main ingredient in diet pill is sibutramine. Sibutramine is appetite suppressant that makes the one who consume it has less appetite, and it turns help them to lose weight.
This chemical once marketed heavily across country. However, later research found out that sibutramine increases cardiovascular activity, making someone has higher chance of getting heart attack or stroke. Because of that reason, several countries such as Australia, China, Canada and European Union prohibited its use.
6. Sildefanil
Sildefanil is a chemical in man strengthener pill. Aside from producing cure and relief to some disease, some pharmaceutical industry also produces strengthener for man stamina. This chemical works by making someone get erected easily, especially those who have problem with their hormone. It works by widening the vein of vital organ.
However, excessive use of it can cause sudden drop of blood rate and can cause unconsciousness to death. Chemicals for such case are only available for use under doctor or expert guidance. Otherwise, the side effect of reckless use may lead to fatal result.
7. Dextrose
Dextrose is glucose elevating agent that works as a medicine to treat patient with low blood pressure. It increases the glucose in someone blood stream and elevate the blood pressure. As far as the production from pharmaceutical industry, dextrose is generally safe under certain dose for both adult and children.
However, excessive consumption can trigger its side effect such as swelling, fever, rapid breathing, blood clot and many more. Thus, someone should only consume dextrose-based drug under certain dose advised by doctor for safer use and result.
8. Fenilbutason
Another chemical that was popular in pharmaceutical industry is fenilbutason. Fenilbutason is analgesic that has similar effect like paracetamol. It works by reducing pain in the body. In the past, fenilbutason also works for horses that just finished race. Nowadays, fenilbutason is no longer an available product in some countries because of its side effect.
Some side effects include the reduction of white blood cells production. In which in turns it lowers the immune system of someone. As a result, someone will get sick easily and therefore should not use it anymore. United States, for example, has withdrawn any pharmaceutical products that has fenilbutason in it.
Other Chemicals Used in Pharmaceutical Industry
Other list of chemicals used in pharmaceutical industry includes:
· Dicalcium Phosphate
· Glucosamine HCl
· Tyrosine
· Valine
Chemical in pharmaceutical industry is critical, but there are always bad side effects when the recipient uses it recklessly. Always read the label and the right dosage to minimize side effects. That is all about chemicals used in pharmaceutical industry.